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当前位置: 首页 > 产品中心 > buffer_solution > EagleBio/iLite ADCC靶向EGFR阳性检测就绪细胞/BM5035
商品详细EagleBio/iLite ADCC靶向EGFR阳性检测就绪细胞/BM5035
EagleBio/iLite ADCC靶向EGFR阳性检测就绪细胞/BM5035
EagleBio/iLite ADCC靶向EGFR阳性检测就绪细胞/BM5035
商品编号: BM5035
品牌: EagleBio
市场价: ¥0.00
美元价: 0.00
产地: 美国(厂家直采)
公司:
产品分类: 缓冲液
公司分类: buffer_solution
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

iLite ADCC Target EGFR Positive Assay Ready Cells

iLite ADCC Target EGFR Positive Assay Ready Cells Developed and Manufactured by Svar Life Science

The Eagle Biosciences iLite Target EGFR (+) Assay Ready Cells are intended for testing:

  • ADCC activity
  • anti-EGFR ADCC activity

Content: >250 μL of Assay Ready Cells suspended in cryoprotective medium from Gibco
Receipt and Storage: Upon receipt confirm that adequate dry-ice is present, and the cells are frozen. Immediately transfer to -80°C storage. Cells should be stored at -80°C (do not store at any other temperature) and are stable as supplied until the expiry date shown. Cells should be used within 30 min of thawing.
For Research Use Only


Key benefits of iLite® Assays

  • Highly specific reporter gene cell lines
  • Very sensitive cell line responses (>10 fold inductions)
  • Assay Ready Cells – ready-to-use from the freezer, without culturing of cells
  • Assays within a workday (typically 4-7 hour assays)
  • Normalization gene, which eliminates unwanted matrix effects

Background

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism whereby pathogenic cells are lysed by lymphocytes, most often Natural Killer (NK) cells. The mechanism involves binding of antibodies to surface antigens on the pathogen. Crosslinking of these antibodies to NK cells through the binding of the Fc-portion to Fc receptors on the NK cells leads to activation of the NK cell and formation of an immune synapse with the pathogenic cell. The NK cell releases cytotoxic granules containing granzymes and perforin into the synapse, leading to apoptosis of the targeted cell (1).


Related Products

iLite Effector V Assay Ready Cells
iLite ADCC Target EGFR (-)
iLite ADCC anti-EGFR Activity Set

品牌介绍
Eagle Biosciences已迅速成为全球研究和临床社区免疫测定,抗体和蛋白质的先进供应商。我们的员工在研究和诊断行业拥有超过25年的经验,在商业化和分销方面拥有超过10年的经验。除了分销来自20多个欧洲组织的产品外,我们还提供EagleBio开发的产品。通过所有这些产品,我们将主要专注于提供有助于医学研究和临床实验室的深奥和创新产品eaglebio新产品介绍FluoBolt-Noggin Fluorescence Immunoassay荧光免疫法SKU:FIA-1702-A6-1分类:骨代谢氟硼酸盐- Noggin Fluorescence Immunoassay是用于定量测定人血清或血浆中NOGGIN的方法。FluoBolt™-Noggin荧光免疫分析与骨肿瘤、强直性脊柱炎和肺动脉高压等疾病有关。